
I received this email from a fellow ID specialist and it made me laugh. Thought I’d share it here:
Written by Mark Crislip, MD, Infectious Diseases, 10:37PM Aug 20, 2012.
Two of my 4 consults today were cellulitis. Common disease. Allow me to pontificate on cellulitis. I am not talking about potential necrotizing fasciitis or processes associated with abscesses. I am talking diffuse erythema with fevers, chills and leukocytosis and no odd risks like swimming in brackish dog spit or something.
The microbiology of cellulitis is complex:
Strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, S. lugdunensis, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, MSSA, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, strep, and MRSA.
That makes for potentially complex treatment regimens. My order, presuming no allergies, for antibiotics in acute cellulitis is
cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, cefazolin, and cefazolin.
With that kind of complexity it is no wonder I see patients on Vancomycin. And Zosin. And meropenem. And Cipro. And clindamycin. I recently heard of a surgeon treating a post op sepsis/wound infection with aztreonam and metronidazole. Make it stop, please make it stop, it burns, it burns soooooooooo much*.
Patience. It takes 3 doses of antibiotic to get therapeutic, so cellulitis will often worsen for 1-2 days on therapy, stabilize for a day, then either recede or fade. Be patient. Don’t order an MRI or CT. Be patient!
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