When I attended the conference last week, one particular talk stood out. I do not think it will ever be erased from my mind! I attended a symposium on the management of Clostridium difficile infection (the bug that cause Pseudomembranous colitis as a result of prolonged antibiotic use).
Nothing has changed with regards to its management. Vancomycin (oral) or Metronidazole are still the mainstay of therapy for the last 2-3 decades as drug companies are reluctant to invest more time and money into this unpleasant adverse effect.
One therapy, according to the speaker, however, works like a charm! Its success rate is well documented to be over 97%!
However, the means of this therapy is anything but desirable! Here is what I mean, take a look:
Here’s the step-by-step on how to perform a fecal transplant!
1. Get a donor (I do not think it will be too difficult ~ it’s pretty ‘crappy’ actually).
2. Screen the donor for C. difficile.
3. Harvest his stool (Eeewwww….gross!). We need 30 g in < 6 hours (that’s a lot of crap)
4. Add 50 ml of 0.9% NS to the above.
5. Blend it in a blender and filter using a coffee filter (preferably not from your kitchen). This reminds of a scene from one of the Austin Powers movie!
6. As for the patient (or victim!), give oral vancomycin and omeprazole.
7. Insert an NG tube into the poor victim above (via the mouth or nostril).
8. Pour item 5 down the tube. (I am about to puke!!!)
9. Cure rate is > 90%.
That’s it! Easy-peasy!
Who says ID conferences are boring?!!!
Thurs, 260608 @ 0700; on call today.